Thursday, November 22, 2012

Extending the mass range of an Orbitrap

I think we've all been hearing rumblings of this for months at all sorts of conferences, but the paper finally showed up in Nature Methods 2 weeks ago.  In this paper, Rose et. al., physically modify an Exactive plus instrument to extend the m/z mass range up to 12,000 Da.  The steps seems predictably complex to this Biologist, but for you engineering types it might not seem that bad.  For this study, I'm sure it didn't hurt that Dr. Makarov himself was one of the co-authors!

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